In rheumatoid arthritis, the incidence of malignancies that are indicated for immune checkpoint inhibitors is increasing.
نویسندگان
چکیده
منابع مشابه
Checkpoint inhibitors in hematological malignancies
Inhibitory molecules such as PD-1, CTLA-4, LAG-3, or TIM-3 play a role to keep a balance in immune function. However, many cancers exploit such molecules to escape immune surveillance. Accumulating data support that their functions are dysregulated in lymphoid neoplasms, including plasma cell myeloma, myelodysplastic syndrome, and acute myeloid leukemia. In lymphoid neoplasms, aberrations in 9p...
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Immune checkpoint blockade in hematologic malignancies.
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ژورنال
عنوان ژورنال: Journal of Global Oncology
سال: 2019
ISSN: 2378-9506
DOI: 10.1200/jgo.2019.5.suppl.72